Preparation of FMD type A87/IRN inactivated vaccine by gamma irradiation and the immune response on guinea pig

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immune response of foot and mouth disease virus type a87/irn inactivated vaccine by gamma irradiation on guinea pig in iran

foot and mouth disease (fmd) is the most contagious disease of cloven-hoofed animals, causingsignificant economical losses in livestock animals. in this study fmd virus type a87/irn was cultured andmultiplied on bhk21 cells. the fmd virus was titrated by the tissue culture infection dose50 method(tcid50 /ml), the virus titration was 107.5.. the fmd virus samples were irradiated and inactivated ...

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Immune Response of Foot and Mouth Disease Virus Type A87/irn Inactivated Vaccine by Gamma Irradiation on Guinea Pig in Iran

Foot and Mouth Disease (FMD) is the most contagious disease of cloven-hoofed animals, causing significant economical losses in livestock animals. In this study FMD Virus type A87/IRN was cultured and multiplied on BHK21 cells. The FMD virus was titrated by the Tissue Culture Infection Dose50 method (TCID50 /ml), the virus titration was 10. The FMD virus samples were irradiated and inactivated b...

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Evaluation of cytokine mRNA expression in vaccinated guinea pigs with foot-and-mouth disease type O inactivated vaccine

Foot-and-mouth disease (FMD) is a severely contagious viral disease that mainly affects cloven-hoofedlivestock and wildlife. This study quantifies the cytokines mRNA expression of vaccinated guinea pigs withFMD type O inactivated vaccine. Blood samples were collected from eight guinea pigs at 7 and 28 days after thefirst vaccination. Extracted mRNAs were reverse-transcribed into cDNA and analyz...

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ژورنال

عنوان ژورنال: Indian Journal of Microbiology

سال: 2008

ISSN: 0046-8991,0973-7715

DOI: 10.1007/s12088-008-0023-4